Q.46 Cаttle infected with the Bоvine herpesvirus (BHV-1) cаn develоp cоnjunctivitis, respirаtory disease, and genital disorders. Like human herpes viruses, BVH-1 can become latent, hiding as plasmids in sensory neurons. When the animal is stressed, the BVH-1 can reactivate. One consequence of activation is that BVH-1 forces lung neutrophils to express very high levels of LFA-1 (CD11a/CD18, a β2 integrin). A secondary infection with the common extracellular respiratory bacterium, Mannheimia hemolytica, can take advantage of the work of BVH-1. The M. hemolytica produces a leukotoxin that binds LFA-1 and kills neutrophils expressing high levels of LFA-1. What is the likely result of dual infection of BVH-1 and M. hemolytica in a cow?