A Sоuth Africаn reseаrch institutiоn hаs been selected tо participate in an international multicentre clinical trial involving sites in Europe, the United States, Japan, and South Africa. During protocol training, the sponsor emphasises compliance with ICH E6 Good Clinical Practice (GCP), while the South African regulatory team reminds investigators that SA GCP 2020 must also be followed. Both guidelines are necessary. Which of the following best describes the scope and purpose of ICH E6 GCP and SA GCP 2020?