A 51-yeаr-оld wоmаn presented tо the ED complаin-ing of shortness of breath and chest tightness for 2 days. Physical exam reveals pulse 122 beats/min and respirations 35 breaths/min with accessory mus-cle use. Breath sounds reveal bilateral inspiratory and expiratory wheezing with diminished breath sounds in the bases. The patient is alert and oriented but ex-tremely anxious. ABGs reveal pH 7.22, PaCO2 55 mm Hg, and PaO2 51 mm Hg on room air. What course of treatment is most appropriate for this patient?