A 34-year-old female presents to the emergency department wi…

Written by Anonymous on August 14, 2026 in Uncategorized with no comments.

Questions

A 34-yeаr-оld femаle presents tо the emergency depаrtment with a twо-month history of progressive muscle weakness. She reports that her symptoms are worse by the end of the day and improve with rest, particularly noting that her eyelids "start drooping" in the evenings and her vision becomes doubled after reading for extended periods. Over the past week, she has also developed difficulty chewing toward the end of meals and occasional slurred speech when she is tired. She denies any sensory changes, numbness, or tingling. She has had no recent illness, trauma, or vaccinations. She denies bowel or bladder dysfunction. On exam: Bilateral ptosis is noted, which worsens with sustained upward gaze for 60 seconds and improves after a brief rest period. Extraocular movements show mild weakness with diplopia on lateral gaze, worse with repetitive testing. Repeated grip strength testing shows normal initial strength that progressively weakens with repetition and improves after rest. Sensory exam is entirely normal, including light touch, pinprick, and proprioception. Deep tendon reflexes are normal and symmetric. No cerebellar signs (no ataxia, no dysmetria). Which of the following is the most likely diagnosis?

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