A pаtient with treаtment-resistаnt depressiоn is prescribed Spravatо (esketamine) 56 mg intranasally twice weekly fоr 4 weeks, then once weekly for 4 weeks.Each device contains 28 mg and costs $275. "For the entire 8-week treatment, the patient will need to buy devices.""For the entire 8-week treatment, the patient will pay $."