Thyroxine (T4) is a hormone that certain animals use to regu…

Written by Anonymous on February 25, 2026 in Uncategorized with no comments.

Questions

Thyrоxine (T4) is а hоrmоne thаt certаin animals use to regulate the activity of cells. The production of T4 depends on the concentrations of two other hormones: thyrotropin releasing hormone (TRH) and thyroid stimulating hormone (TSH).  TRH comes from a part of the brain called the hypothalamus. This hormone can bind to receptors in another part of the brain, called the pituitary gland. Upon binding to a receptor, TRH activates a signaling pathway that causes a cell to release TSH.  The figure shows the signaling pathway that controls the production of T4. TSH binds to receptors in the thyroid gland, causing cells of this gland to produce T4. The production of T4 depends on an enzyme called thyroid peroxidase (TPO), which creates T4 by adding an iodide ion (I-) to a molecule.  A nonpolar structure enables T4 to diffuse through the phospholipid bilayer of any cell, including cells of the hypothalamus and the pituitary gland, where T4 inhibits the release of TRH and TSH, respectively. Choose the word or phrase that accurately completes the following sentence. When TSH binds to a receptor, the concentration of cAMP in a cell should ______.

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